Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer

Gastric Cancer is one of the most lethal malignancies worldwide. Gamma-glutamyl transpeptidase (GGT) is an enzyme mainly involved in cellular glutathione homeostasis. We aim to explore the clinical value of GGT in gastric cancer. Among 322 patients enrolled, 65/82 patients were determined as GGT pos...

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Veröffentlicht in:	Oncotarget 2017-05, Vol.8 (22), p.36171-36184
Hauptverfasser:	Wang, Qinchuan, Shu, Xiang, Dong, Yong, Zhou, Jichun, Teng, Rongyue, Shen, Jianguo, Chen, Yongxia, Dong, Mingjun, Zhang, Wenjun, Huang, Yasheng, Xie, Shuduo, Wei, Qun, Zhao, Wenhe, Chen, Wenjun, Yuan, Xiaoming, Qi, Xu, Wang, Linbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - metabolism Carcinogenesis Female gamma-Glutamyltransferase - genetics gamma-Glutamyltransferase - metabolism Glutathione - metabolism Humans Lymphatic Metastasis Male Middle Aged Prognosis Proto-Oncogene Proteins p21(ras) - genetics Proto-Oncogene Proteins p21(ras) - metabolism Receptor, ErbB-2 - genetics Receptor, ErbB-2 - metabolism Research Paper Retrospective Studies Stomach Neoplasms - diagnosis Stomach Neoplasms - genetics Stomach Neoplasms - mortality Survival Analysis
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