Melding a New 3-Dimensional Agarose Colony Assay with the Emax Model to Determine the Effects of Drug Combinations on Cancer Cells

The goal of our study was two-fold: (i) develop a robust 3D colony assay methodology to interrogate drug combinations using GelCount™ and (ii) to develop 2-drug combinations that might be useful in the clinic for the treatment of high-grade gliomas. We used three glioma cell lines (U251MG, SNB19, an...

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Veröffentlicht in:	Technology in cancer research & treatment 2009-04, Vol.8 (2), p.163-175
Hauptverfasser:	Kajiwara, Yoshinori, Panchabhai, Sonali, Liu, Diane D., Kong, Maiying, Lee, J. Jack, Levin, Victor A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Medical sciences Neurology Tumors of the nervous system. Phacomatoses
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