Evaluation of non-thermal plasma-induced anticancer effects on human colon cancer cells

Evaluation of non-thermal plasma-induced anticancer effects on human colon cancer cells

Non-thermal atmospheric-pressure plasma has been introduced in various applications such as sterilization, wound healing, blood coagulation, and other biomedical applications. The most attractive application of non-thermal atmospheric-pressure plasma is in cancer treatment, where the plasma is used...

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Veröffentlicht in:Biomedical optics express 2017-05, Vol.8 (5), p.2649-2659
Hauptverfasser: Choi, Jae-Sun, Kim, Jeongho, Hong, Young-Jun, Bae, Woom-Yee, Choi, Eun Ha, Jeong, Joo-Won, Park, Hun-Kuk
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container_issue 5
container_start_page 2649
container_title Biomedical optics express
container_volume 8
creator Choi, Jae-Sun
Kim, Jeongho
Hong, Young-Jun
Bae, Woom-Yee
Choi, Eun Ha
Jeong, Joo-Won
Park, Hun-Kuk
description Non-thermal atmospheric-pressure plasma has been introduced in various applications such as sterilization, wound healing, blood coagulation, and other biomedical applications. The most attractive application of non-thermal atmospheric-pressure plasma is in cancer treatment, where the plasma is used to produce reactive oxygen species (ROS) to facilitate cell apoptosis. We investigate the effects of different durations of exposure to dielectric-barrier discharge (DBD) plasma on colon cancer cells using measurement of cell viability and ROS levels, western blot, immunocytochemistry, and Raman spectroscopy. Our results suggest that different kinds of plasma-treated cells can be differentiated from control cells using the Raman data.
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title Evaluation of non-thermal plasma-induced anticancer effects on human colon cancer cells
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