Endocytosis of tight junction proteins and the regulation of degradation and recycling

Internalization of tight junction (TJ) proteins from the plasma membrane is a pivotal mechanism regulating TJ plasticity and function in both epithelial and endothelial barrier tissues. Once internalized, the TJ proteins enter complex vesicular machinery, where further trafficking is directly depend...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Annals of the New York Academy of Sciences 2017-06, Vol.1397 (1), p.54-65
Hauptverfasser:	Stamatovic, Svetlana M., Johnson, Allison M., Sladojevic, Nikola, Keep, Richard F., Andjelkovic, Anuska V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals claudin Claudin-1 - metabolism Degradation Drug delivery Drug delivery systems early endosomes Endocytosis Endosomes Endosomes - metabolism Endothelial cells Endothelial Cells - metabolism Epithelial Cells - metabolism Humans Internalization late endosomes Machinery and equipment Models, Biological Permeability Plastic properties Plasticity Protein turnover Proteins recycling Tight Junction Proteins - metabolism Tight Junctions - metabolism Tissues Waste management
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!