NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo expansion

Infusion of allogeneic NK cells is a potential immunotherapy for both hematopoietic malignancies and solid tumors. Interactions between killer immunoglobulin-like receptors (KIR) on human NK cells and KIR-ligands on tumor cells influence the magnitude of NK function. To obtain sufficient numbers of...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cancer immunology, immunotherapy : CII immunotherapy : CII, 2016-07, Vol.65 (9), p.1047-1059
Hauptverfasser:	Wang, Wei, Erbe, Amy K, Alderson, Kory A, Phillips, Emily, Gallenberger, Mikayla, Gan, Jacek, Campana, Dario, Hank, Jacquelyn A, Sondel, Paul M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!