Conjugating a groove-binding motif to an Ir() complex for the enhancement of G-quadruplex probe behavior

In this study, the reported G-quadruplex groove binder benzo[ d , e ]isoquinoline was linked to a cyclometallated Ir( iii ) complex to generate a highly selective DNA probe 1 that retains the favorable photophysical properties of the parent complex. The linked complex 1 showed advantages of both par...

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Veröffentlicht in:	Chemical science (Cambridge) 2016-01, Vol.7 (4), p.2516-2523
Hauptverfasser:	Wang, Modi, Mao, Zhifeng, Kang, Tian-Shu, Wong, Chun-Yuen, Mergny, Jean-Louis, Leung, Chung-Hang, Ma, Dik-Lung
Format:	Artikel
Sprache:	eng
Schlagworte:	Binders Chemistry Conjugation Coordination compounds Deoxyribonucleic acid Fluorescence Grooves Parents Phosphorescence
Online-Zugang:	Volltext
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