β2-Adrenergic receptor activation mobilizes intracellular calcium via a non-canonical cAMP-independent signaling pathway

Beta adrenergic receptors (βARs) are G-protein-coupled receptors essential for physiological responses to the hormones/neurotransmitters epinephrine and norepinephrine which are found in the nervous system and throughout the body. They are the targets of numerous widely used drugs, especially in the...

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Veröffentlicht in:	The Journal of biological chemistry 2017-06, Vol.292 (24), p.9967-9974
Hauptverfasser:	Galaz-Montoya, Monica, Wright, Sara J., Rodriguez, Gustavo J., Lichtarge, Olivier, Wensel, Theodore G.
Format:	Artikel
Sprache:	eng
Schlagworte:	adrenergic receptor calcium intracellular release cell signaling cyclic AMP (cAMP) G-protein-coupled receptor (GPCR) Signal Transduction β2-adrenergic receptor
Online-Zugang:	Volltext
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