Identification and characterization of RASSF1C piRNA target genes in lung cancer cells

RASSF1C up-regulates important genes involved in lung cancer cell growth, including a stem cell self-renewal gene, piwil1. In this article, we report the identification of small noncoding PIWI-interacting RNAs (piRNAs) in lung cancer cells over-expressing RASSF1C. A piRNA microarray screen was perfo...

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Veröffentlicht in:	Oncotarget 2017-05, Vol.8 (21), p.34268-34282
Hauptverfasser:	Reeves, Mark E, Firek, Mathew, Jliedi, Abdullaati, Amaar, Yousef G
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Adenylate Kinase - genetics Cell Line, Tumor Cell Proliferation Female Gene Expression Regulation, Neoplastic Gene Regulatory Networks Humans Lung Neoplasms - genetics Oligonucleotide Array Sequence Analysis Research Paper RNA, Small Interfering - genetics Tumor Suppressor Proteins - genetics Up-Regulation
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