Ultrasensitive Phototriggered Local Anesthesia

An injectable local anesthetic producing repeatable on-demand nerve block would be desirable for pain management. Here we present a phototriggerable device to achieve repeatable and adjustable on-demand local anesthesia in superficial or deep tissues, consisting of gold nanorods attached to low temp...

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Veröffentlicht in:	Nano letters 2017-02, Vol.17 (2), p.660-665
Hauptverfasser:	Zhan, Changyou, Wang, Weiping, Santamaria, Claudia, Wang, Bruce, Rwei, Alina, Timko, Brian P, Kohane, Daniel S
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia, Local - instrumentation Anesthesia, Local - methods Animals Dexmedetomidine - chemistry Dexmedetomidine - pharmacology Drug Liberation Gold Infrared Rays Light Liposomes - chemistry Liposomes - radiation effects Nanotubes - chemistry Nanotubes - radiation effects Nerve Block - instrumentation Nerve Block - methods Particle Size Rats Sciatic Nerve Surface Properties Tetrodotoxin - chemistry Tetrodotoxin - pharmacology Tissue Distribution
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