Overexpression of NOX4 predicts poor prognosis and promotes tumor progression in human colorectal cancer

NADPH oxidase 4 (NOX4), a major source of reactive oxygen species (ROS) production, has been increasingly reported to be involved in tumorigenesis and/or tumor progression, but limited data are available regarding the role of NOX4 in colorectal carcinoma (CRC). We retrieved six independent investiga...

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Veröffentlicht in:	Oncotarget 2017-05, Vol.8 (20), p.33586-33600
Hauptverfasser:	Lin, Xiao-Lu, Yang, Li, Fu, Seng-Wang, Lin, Wen-Feng, Gao, Yun-Jie, Chen, Hao-Yan, Ge, Zhi-Zheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Apoptosis - genetics Cell Line, Tumor Cell Movement - genetics Cell Proliferation Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Computational Biology - methods Databases, Nucleic Acid Disease Progression Epithelial-Mesenchymal Transition - genetics Female Follow-Up Studies Gene Expression Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Kaplan-Meier Estimate Male Middle Aged NADPH Oxidase 4 - genetics Neoplasm Grading Neoplasm Metastasis Neoplasm Staging Prognosis Research Paper ROC Curve
Online-Zugang:	Volltext
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