Assessment of the interlaboratory variability and robustness of JAK2V617F mutation assays: A study involving a consortium of 19 Italian laboratories

To date, a plenty of techniques for the detection of JAK2V617F is used over different laboratories, with substantial differences in specificity and sensitivity. Therefore, to provide reliable and comparable results, the standardization of molecular techniques is mandatory.A network of 19 centers was...

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Veröffentlicht in:	Oncotarget 2017-05, Vol.8 (20), p.32608-32617
Hauptverfasser:	Perricone, Margherita, Palandri, Francesca, Ottaviani, Emanuela, Angelini, Mario, Bagli, Laura, Bellesia, Enrica, Donati, Meris, Gemmati, Donato, Zucchini, Patrizia, Mancini, Stefania, Marchica, Valentina, Trubini, Serena, De Matteis, Giovanna, Di Zacomo, Silvia, Favarato, Mosè, Fioroni, Annamaria, Bolzonella, Caterina, Maccari, Giorgia, Navaglia, Filippo, Gatti, Daniela, Toffolatti, Luisa, Orlandi, Linda, Laloux, Vèronique, Manfrini, Marco, Galieni, Piero, Giannini, Barbara, Tieghi, Alessia, Barulli, Sara, Serino, Maria Luisa, Maccaferri, Monica, Scortechini, Anna Rita, Giuliani, Nicola, Vallisa, Daniele, Bonifacio, Massimiliano, Accorsi, Patrizia, Salbe, Cristina, Fazio, Vinicio, Gusella, Milena, Toffoletti, Eleonora, Salvucci, Marzia, Svaldi, Mirija, Gherlinzoni, Filippo, Cassavia, Francesca, Orsini, Francesco, Martinelli, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA Mutational Analysis - methods DNA Mutational Analysis - standards Humans Italy Janus Kinase 2 - genetics Janus Kinase 2 - metabolism Laboratories - standards Laboratories - statistics & numerical data Mutation Myeloproliferative Disorders - enzymology Myeloproliferative Disorders - genetics Observer Variation Research Paper
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