Dopamine neurons encode performance error in singing birds
Many behaviors are learned through trial and error by matching performance to internal goals. Yet neural mechanisms of performance evaluation remain poorly understood. We recorded basal ganglia—projecting dopamine neurons in singing zebra finches as we controlled perceived song quality with distorte...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 2016-12, Vol.354 (6317), p.1278-1282 |
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| container_title | Science (American Association for the Advancement of Science) |
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| creator | Gadagkar, Vikram Puzerey, Pavel A. Chen, Ruidong Baird-Daniel, Eliza Farhang, Alexander R. Goldberg, Jesse H. |
| description | Many behaviors are learned through trial and error by matching performance to internal goals. Yet neural mechanisms of performance evaluation remain poorly understood. We recorded basal ganglia—projecting dopamine neurons in singing zebra finches as we controlled perceived song quality with distorted auditory feedback. Dopamine activity was phasically suppressed after distorted syllables, consistent with a worse-than-predicted outcome, and was phasically activated at the precise moment of the song when a predicted distortion did not occur, consistent with a better-than-predicted outcome. Error response magnitude depended on distortion probability. Thus, dopaminergic error signals can evaluate behaviors that are not learned for reward and are instead learned by matching performance outcomes to internal goals. |
| doi_str_mv | 10.1126/science.aah6837 |
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| subjects | Animal communication Animals Basal Ganglia - cytology Basal Ganglia - physiology Birds Brain Cellular biology Control systems Control theory Distortion Dopamine Dopamine - physiology Dopaminergic Neurons - physiology Errors Feedback Finches Learning - physiology Male Reward Singing Taeniopygia guttata Vocalization, Animal - physiology |
| title | Dopamine neurons encode performance error in singing birds |
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