Low-dose systemic scopolamine disrupts context conditioning in rats

Cholinergic neurotransmission plays a key role in learning and memory. Prior research with rats indicated that a low dose of pre-training scopolamine (0.1 mg/kg), a cholinergic receptor antagonist, did not affect cued fear conditioning, but did block renewal when injected before extinguishing a cond...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of psychopharmacology (Oxford) 2017-06, Vol.31 (6), p.667-673
Hauptverfasser:	Luyten, Laura, Nuyts, Shauni, Beckers, Tom
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors Animals Anxiety Aversion learning Cholinergic Antagonists - pharmacology Conditioning Conditioning, Classical - drug effects Cues Disruption Electroshock - methods Extinguishing Fear - drug effects Fear conditioning Hippocampus Hippocampus - drug effects Learning - drug effects Male Memory Memory - drug effects Neurotransmission Rats Rats, Wistar Rodents Scopolamine Scopolamine - pharmacology Serial learning Translating
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!