Elevated serum tetrac in Graves’ disease: potential pathogenic role in thyroid-associated ophthalmopathy

Context: The sources and biological impact of 3,3’,5,5’ tetraiodothyroacetic acid (TA4) are uncertain. CD34+ fibrocytes express several proteins involved in the production of thyroid hormones. They infiltrate the orbit in Graves’ disease (GD), an autoimmune process known as thyroid-associated ophtha...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2017-03, Vol.102 (3), p.776-785
Hauptverfasser:	Fernando, Roshini, Placzek, Ekaterina, Reese, Edmund A, Placzek, Andrew T, Schwartz, Samantha, Trierweiler, Aaron, Niziol, Leslie M, Atkins, Stephen, Scanlan, Thomas S, Smith, Terry J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Autoradiography Case-Control Studies CD34 antigen Cell culture Cells, Cultured Chromatography, Liquid Clinical s Ependymoglial Cells - metabolism Epithelial cells Female Fibroblasts Fibroblasts - metabolism Flow Cytometry Glucuronosyltransferase - metabolism Graves Disease - blood Graves Disease - complications Graves Ophthalmopathy - blood Graves Ophthalmopathy - etiology Graves' disease Health care facilities HeLa Cells Humans Hyaluronan synthase Hyaluronan Synthases Hyaluronic acid Hyaluronic Acid - metabolism Immunoassay Immunoglobulins Immunoglobulins, Thyroid-Stimulating - metabolism Interleukin 6 Interleukin-6 - metabolism Liquid chromatography Male Mass spectrometry Mass spectroscopy Middle Aged Orbit Pathogenesis Polymerase chain reaction Propylthiouracil Prostaglandin-Endoperoxide Synthases - metabolism Proteins Real-Time Polymerase Chain Reaction Receptors, Thyrotropin - metabolism Retina Retinal Pigment Epithelium - cytology Retinal Pigment Epithelium - metabolism Serum levels Sex Factors Stem cells Tandem Mass Spectrometry Thyroid gland Thyroid hormones Thyroid-stimulating hormone Thyrotropin - metabolism Thyroxine Thyroxine - analogs & derivatives Thyroxine - blood Triiodothyronine Triiodothyronine - blood Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!