A Review of the Impact of Maternal Obesity on the Cognitive Function and Mental Health of the Offspring
Globally, more than 20% of women of reproductive age are currently estimated to be obese. Children born to obese mothers are at higher risk of developing obesity, coronary heart disease, diabetes, stroke, and asthma in adulthood. Increasing clinical and experimental evidence suggests that maternal o...
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| Veröffentlicht in: | International journal of molecular sciences 2017-05, Vol.18 (5), p.1093 |
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| container_title | International journal of molecular sciences |
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| creator | Contu, Laura Hawkes, Cheryl A |
| description | Globally, more than 20% of women of reproductive age are currently estimated to be obese. Children born to obese mothers are at higher risk of developing obesity, coronary heart disease, diabetes, stroke, and asthma in adulthood. Increasing clinical and experimental evidence suggests that maternal obesity also affects the health and function of the offspring brain across the lifespan. This review summarizes the current findings from human and animal studies that detail the impact of maternal obesity on aspects of learning, memory, motivation, affective disorders, attention-deficit hyperactivity disorder, autism spectrum disorders, and neurodegeneration in the offspring. Epigenetic mechanisms that may contribute to this mother-child interaction are also discussed. |
| doi_str_mv | 10.3390/ijms18051093 |
| format | Article |
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Children born to obese mothers are at higher risk of developing obesity, coronary heart disease, diabetes, stroke, and asthma in adulthood. Increasing clinical and experimental evidence suggests that maternal obesity also affects the health and function of the offspring brain across the lifespan. This review summarizes the current findings from human and animal studies that detail the impact of maternal obesity on aspects of learning, memory, motivation, affective disorders, attention-deficit hyperactivity disorder, autism spectrum disorders, and neurodegeneration in the offspring. 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| subjects | Affective disorders Animals Attention Deficit Disorder with Hyperactivity - etiology Attention deficit hyperactivity disorder Autism Autism Spectrum Disorder - etiology Aversion learning Cardiovascular disease Children Cognition Coronary artery disease Diabetes mellitus Diet, High-Fat - adverse effects Female Heart diseases Humans Hyperactivity Life span Memory Mental disorders Mental Health Mood Disorders - etiology Mothers Motivation Neurodegeneration Neurodegenerative Diseases - etiology Neurodevelopmental Disorders - etiology Obesity Obesity - complications Obesity - etiology Pregnancy Pregnancy Complications - etiology Prenatal Exposure Delayed Effects - etiology Review Risk Serial learning Stroke |
| title | A Review of the Impact of Maternal Obesity on the Cognitive Function and Mental Health of the Offspring |
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