Oral Mucositis: Melatonin Gel an Effective New Treatment
The current treatment for cervico-facial cancer involves radio and/or chemotherapy. Unfortunately, cancer therapies can lead to local and systemic complications such as mucositis, which is the most common dose-dependent complication in the oral cavity and gastrointestinal tract. Mucositis can cause...
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| Veröffentlicht in: | International journal of molecular sciences 2017-05, Vol.18 (5), p.1003 |
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| container_issue | 5 |
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| container_title | International journal of molecular sciences |
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| creator | Abdel Moneim, Ahmed Esmat Guerra-Librero, Ana Florido, Javier Shen, Ying-Qiang Fernández-Gil, Beatriz Acuña-Castroviejo, Darío Escames, Germaine |
| description | The current treatment for cervico-facial cancer involves radio and/or chemotherapy. Unfortunately, cancer therapies can lead to local and systemic complications such as mucositis, which is the most common dose-dependent complication in the oral cavity and gastrointestinal tract. Mucositis can cause a considerably reduced quality of life in cancer patients already suffering from physical and psychological exhaustion. However, the role of melatonin in the treatment of mucositis has recently been investigated, and offers an effective alternative therapy in the prevention and/or management of radio and/or chemotherapy-induced mucositis. This review focuses on the pathobiology and management of mucositis in order to improve the quality of cancer patients' lives. |
| doi_str_mv | 10.3390/ijms18051003 |
| format | Article |
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Unfortunately, cancer therapies can lead to local and systemic complications such as mucositis, which is the most common dose-dependent complication in the oral cavity and gastrointestinal tract. Mucositis can cause a considerably reduced quality of life in cancer patients already suffering from physical and psychological exhaustion. However, the role of melatonin in the treatment of mucositis has recently been investigated, and offers an effective alternative therapy in the prevention and/or management of radio and/or chemotherapy-induced mucositis. 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| subjects | Animals Antioxidants - administration & dosage Antioxidants - therapeutic use Cancer Cancer therapies Chemotherapy Exhaustion Gastrointestinal tract Gels - chemistry Humans Melatonin Melatonin - administration & dosage Melatonin - therapeutic use Mucositis Oral cavity Patients Quality of life Review Stomatitis - drug therapy Stomatitis - etiology |
| title | Oral Mucositis: Melatonin Gel an Effective New Treatment |
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