A randomised controlled trial assessing the efficacy of co-phenylcaine nasal spray in flexible transnasal pharyngolaryngoscopy
INTRODUCTION The aim of this study was to assess whether using co-phenylcaine nasal spray before flexible transnasal pharyngolaryngoscopy results in reduced pain and discomfort during the procedure. METHODS This was a randomised controlled trial. Eighty-four patients were randomised to receive eithe...
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| Veröffentlicht in: | Annals of the Royal College of Surgeons of England 2017-04, Vol.99 (4), p.313-318 |
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| creator | Javed, F Parmar, A Hussain, A Hajioff, D Pinder, D |
| description | INTRODUCTION The aim of this study was to assess whether using co-phenylcaine nasal spray before flexible transnasal pharyngolaryngoscopy results in reduced pain and discomfort during the procedure. METHODS This was a randomised controlled trial. Eighty-four patients were randomised to receive either co-phenylcaine nasal spray or placebo nasal spray before performing transnasal flexible pharyngolaryngoscopy. Patient reported outcome measures included pain, discomfort, unpleasantness and willingness to repeat the procedure while clinician reported outcome measures comprised ease of examination and quality of view obtained during the procedure. RESULTS There was no statistically significant difference in scores for pain, discomfort, unpleasantness and willingness to repeat the procedure between the co-phenylcaine and placebo groups. On the other hand, ease of examination scores were significantly better for the co-phenylcaine group than for the placebo group. CONCLUSIONS The majority of patients do not find flexible pharyngolaryngoscopy unpleasant or painful with or without topical nasal anaesthesia. However, the spray does appear to help the examiner in completing a satisfactory assessment. |
| doi_str_mv | 10.1308/rcsann.2016.0336 |
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METHODS This was a randomised controlled trial. Eighty-four patients were randomised to receive either co-phenylcaine nasal spray or placebo nasal spray before performing transnasal flexible pharyngolaryngoscopy. Patient reported outcome measures included pain, discomfort, unpleasantness and willingness to repeat the procedure while clinician reported outcome measures comprised ease of examination and quality of view obtained during the procedure. RESULTS There was no statistically significant difference in scores for pain, discomfort, unpleasantness and willingness to repeat the procedure between the co-phenylcaine and placebo groups. On the other hand, ease of examination scores were significantly better for the co-phenylcaine group than for the placebo group. CONCLUSIONS The majority of patients do not find flexible pharyngolaryngoscopy unpleasant or painful with or without topical nasal anaesthesia. However, the spray does appear to help the examiner in completing a satisfactory assessment.</description><identifier>ISSN: 0035-8843</identifier><identifier>EISSN: 1478-7083</identifier><identifier>DOI: 10.1308/rcsann.2016.0336</identifier><identifier>PMID: 27869488</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Administration, Topical ; Adult ; Aged ; Aged, 80 and over ; Anesthesia ; Anesthetics, Local - therapeutic use ; Double-Blind Method ; Drug Combinations ; Endoscopy ; Female ; Humans ; Laryngoscopy - methods ; Lidocaine - therapeutic use ; Male ; Middle Aged ; Nasal Cavity ; Nasal Decongestants - therapeutic use ; Nasal Sprays ; Natural Orifice Endoscopic Surgery ; Nose ; Otolaryngology ; Pain ; Pain - prevention & control ; Patients ; Performance evaluation ; Phenylephrine - therapeutic use ; Studies ; Young Adult</subject><ispartof>Annals of the Royal College of Surgeons of England, 2017-04, Vol.99 (4), p.313-318</ispartof><rights>Copyright Royal College of Surgeons of England Apr 2017</rights><rights>Copyright © 2017, All rights reserved by the Royal College of Surgeons of England 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c424t-d4c1d6e98456c9f8cf3d8be095735f9fa1c43e945a4b61c24c10d7308b5729db3</citedby><cites>FETCH-LOGICAL-c424t-d4c1d6e98456c9f8cf3d8be095735f9fa1c43e945a4b61c24c10d7308b5729db3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449676/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449676/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,725,778,782,883,27911,27912,53778,53780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27869488$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Javed, F</creatorcontrib><creatorcontrib>Parmar, A</creatorcontrib><creatorcontrib>Hussain, A</creatorcontrib><creatorcontrib>Hajioff, D</creatorcontrib><creatorcontrib>Pinder, D</creatorcontrib><title>A randomised controlled trial assessing the efficacy of co-phenylcaine nasal spray in flexible transnasal pharyngolaryngoscopy</title><title>Annals of the Royal College of Surgeons of England</title><addtitle>Ann R Coll Surg Engl</addtitle><description>INTRODUCTION The aim of this study was to assess whether using co-phenylcaine nasal spray before flexible transnasal pharyngolaryngoscopy results in reduced pain and discomfort during the procedure. METHODS This was a randomised controlled trial. Eighty-four patients were randomised to receive either co-phenylcaine nasal spray or placebo nasal spray before performing transnasal flexible pharyngolaryngoscopy. Patient reported outcome measures included pain, discomfort, unpleasantness and willingness to repeat the procedure while clinician reported outcome measures comprised ease of examination and quality of view obtained during the procedure. RESULTS There was no statistically significant difference in scores for pain, discomfort, unpleasantness and willingness to repeat the procedure between the co-phenylcaine and placebo groups. On the other hand, ease of examination scores were significantly better for the co-phenylcaine group than for the placebo group. CONCLUSIONS The majority of patients do not find flexible pharyngolaryngoscopy unpleasant or painful with or without topical nasal anaesthesia. However, the spray does appear to help the examiner in completing a satisfactory assessment.</description><subject>Administration, Topical</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anesthesia</subject><subject>Anesthetics, Local - therapeutic use</subject><subject>Double-Blind Method</subject><subject>Drug Combinations</subject><subject>Endoscopy</subject><subject>Female</subject><subject>Humans</subject><subject>Laryngoscopy - methods</subject><subject>Lidocaine - therapeutic use</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nasal Cavity</subject><subject>Nasal Decongestants - therapeutic use</subject><subject>Nasal Sprays</subject><subject>Natural Orifice Endoscopic Surgery</subject><subject>Nose</subject><subject>Otolaryngology</subject><subject>Pain</subject><subject>Pain - prevention & control</subject><subject>Patients</subject><subject>Performance evaluation</subject><subject>Phenylephrine - therapeutic use</subject><subject>Studies</subject><subject>Young Adult</subject><issn>0035-8843</issn><issn>1478-7083</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkUFv1DAQhS0EotuWOycUiQuXLHZsx_YFqaqgIFXiQs-W44x3XXntYGcRufDb61VKBT3NSPPN07x5CL0leEsolh-zLSbGbYdJv8WU9i_QhjAhW4ElfYk2GFPeSsnoGTov5R5jooQkr9FZJ2SvmJQb9OeqySaO6eALjI1Ncc4phNrO2ZvQmFKgFB93zbyHBpzz1tilSa6i7bSHuARrfIQmmlLxMmWzND42LsBvPwSoMiaWdTjtTV7iLoW1FJum5RK9ciYUePNYL9Ddl88_rr-2t99vvl1f3baWdWxuR2bJ2IOSjPdWOWkdHeUAWHFBuVPOEMsoKMYNG3piu4rjUdQPDVx0ahzoBfq06k7H4QCjherTBD1lf6jX6GS8_n8S_V7v0i_NGVO96KvAh0eBnH4eocy6fsxCCCZCOhZNJOs4x1iIir5_ht6nY47VniZKYXl6PK4UXimbUykZ3NMxBOtTuHoNV5_C1adw68q7f008LfxNkz4AaNelog</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>Javed, F</creator><creator>Parmar, A</creator><creator>Hussain, A</creator><creator>Hajioff, D</creator><creator>Pinder, D</creator><general>BMJ Publishing Group LTD</general><general>Royal College of Surgeons</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>EHMNL</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170401</creationdate><title>A randomised controlled trial assessing the efficacy of co-phenylcaine nasal spray in flexible transnasal pharyngolaryngoscopy</title><author>Javed, F ; Parmar, A ; Hussain, A ; Hajioff, D ; Pinder, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c424t-d4c1d6e98456c9f8cf3d8be095735f9fa1c43e945a4b61c24c10d7308b5729db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Administration, Topical</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anesthesia</topic><topic>Anesthetics, Local - therapeutic use</topic><topic>Double-Blind Method</topic><topic>Drug Combinations</topic><topic>Endoscopy</topic><topic>Female</topic><topic>Humans</topic><topic>Laryngoscopy - methods</topic><topic>Lidocaine - therapeutic use</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nasal Cavity</topic><topic>Nasal Decongestants - therapeutic use</topic><topic>Nasal Sprays</topic><topic>Natural Orifice Endoscopic Surgery</topic><topic>Nose</topic><topic>Otolaryngology</topic><topic>Pain</topic><topic>Pain - prevention & control</topic><topic>Patients</topic><topic>Performance evaluation</topic><topic>Phenylephrine - therapeutic use</topic><topic>Studies</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Javed, F</creatorcontrib><creatorcontrib>Parmar, A</creatorcontrib><creatorcontrib>Hussain, A</creatorcontrib><creatorcontrib>Hajioff, D</creatorcontrib><creatorcontrib>Pinder, D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>UK & Ireland Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of the Royal College of Surgeons of England</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Javed, F</au><au>Parmar, A</au><au>Hussain, A</au><au>Hajioff, D</au><au>Pinder, D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A randomised controlled trial assessing the efficacy of co-phenylcaine nasal spray in flexible transnasal pharyngolaryngoscopy</atitle><jtitle>Annals of the Royal College of Surgeons of England</jtitle><addtitle>Ann R Coll Surg Engl</addtitle><date>2017-04-01</date><risdate>2017</risdate><volume>99</volume><issue>4</issue><spage>313</spage><epage>318</epage><pages>313-318</pages><issn>0035-8843</issn><eissn>1478-7083</eissn><abstract>INTRODUCTION The aim of this study was to assess whether using co-phenylcaine nasal spray before flexible transnasal pharyngolaryngoscopy results in reduced pain and discomfort during the procedure. METHODS This was a randomised controlled trial. Eighty-four patients were randomised to receive either co-phenylcaine nasal spray or placebo nasal spray before performing transnasal flexible pharyngolaryngoscopy. Patient reported outcome measures included pain, discomfort, unpleasantness and willingness to repeat the procedure while clinician reported outcome measures comprised ease of examination and quality of view obtained during the procedure. RESULTS There was no statistically significant difference in scores for pain, discomfort, unpleasantness and willingness to repeat the procedure between the co-phenylcaine and placebo groups. On the other hand, ease of examination scores were significantly better for the co-phenylcaine group than for the placebo group. CONCLUSIONS The majority of patients do not find flexible pharyngolaryngoscopy unpleasant or painful with or without topical nasal anaesthesia. 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| subjects | Administration, Topical Adult Aged Aged, 80 and over Anesthesia Anesthetics, Local - therapeutic use Double-Blind Method Drug Combinations Endoscopy Female Humans Laryngoscopy - methods Lidocaine - therapeutic use Male Middle Aged Nasal Cavity Nasal Decongestants - therapeutic use Nasal Sprays Natural Orifice Endoscopic Surgery Nose Otolaryngology Pain Pain - prevention & control Patients Performance evaluation Phenylephrine - therapeutic use Studies Young Adult |
| title | A randomised controlled trial assessing the efficacy of co-phenylcaine nasal spray in flexible transnasal pharyngolaryngoscopy |
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