Preparation and Identification of HER2 Radioactive Ligands and Imaging Study of Breast Cancer-Bearing Nude Mice1

OBJECTIVE: A micro-molecule peptide TP1623 of 99m Tc-human epithelial growth factor receptor 2 (HER2) was prepared and the feasibility of using it as a HER2-positive molecular imaging agent for breast cancer was evaluated. METHODS: TP1623 was chemically synthesized and labeled with 99m Tc. The label...

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Veröffentlicht in:Translational oncology 2017-05, Vol.10 (4), p.518-526
Hauptverfasser: Zhang, Meng-zhi, Guan, Yan-xing, Zhong, Jin-xiu, Chen, Xue-zhong
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Sprache:eng
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