FGF Signaling Prevents the Terminal Differentiation of Odontoblasts

Members of the fibroblast growth factor (FGF) family play essential and important roles in primary and reparative dentinogenesis, with conflicting results regarding their effects on odontoblast differentiation. Our recent studies showed that the effects of FGF2 on cells in odontoblast lineage were s...

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Veröffentlicht in:	Journal of dental research 2017-06, Vol.96 (6), p.663-670
Hauptverfasser:	Sagomonyants, K., Kalajzic, I., Maye, P., Mina, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Morphogenetic Proteins - metabolism Butadienes - pharmacology Carrier Proteins - pharmacology Cell differentiation Cell Differentiation - drug effects Cells, Cultured Dental pulp Dental Pulp - cytology Dental Pulp - drug effects Dentinogenesis Dentinogenesis - drug effects Dentinogenesis - physiology Dentistry Extracellular Matrix Proteins - metabolism Fibroblast growth factor 2 Fibroblast Growth Factor 2 - pharmacology Fibroblast growth factor receptors Gene expression Green fluorescent protein Immunohistochemistry Kinases Mice Mineralization Molecular modelling Nitriles - pharmacology Odontoblasts Odontoblasts - cytology Odontoblasts - drug effects Osteogenesis Phosphoproteins - metabolism Proteins Pyrroles - pharmacology Real-Time Polymerase Chain Reaction Research Reports Sialoglycoproteins - metabolism Signal Transduction Stem cells Transgenes Transgenic animals Transgenic mice
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