Concise Review: Hematopoietic Stem Cell Origins: Lessons from Embryogenesis for Improving Regenerative Medicine

Hematopoietic stem cells (HSCs) have extensive regenerative capacity to replace all blood cell types, an ability that is harnessed in the clinic for bone marrow transplantation. Finding appropriate donors remains a major limitation to more extensive usage of HSC‐based therapies. Derivation of patien...

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Veröffentlicht in:	Stem cells translational medicine 2017-01, Vol.6 (1), p.60-67
Hauptverfasser:	De La Garza, Adriana, Sinha, Arpan, Bowman, Teresa V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Blood Bone marrow Bone marrow transplant Bone marrow transplantation Cell Lineage Coronary vessels Developmental biology Embryo Embryogenesis Embryonic Development Gene expression Hematopoietic stem cells Hematopoietic Stem Cells - cytology Humans Inflammation - pathology Mammals Pluripotency Receptors, Notch - metabolism Regeneration Regenerative Medicine Stem cell transplantation Stem cells Studies Tissue‐Specific Progenitor and Stem Cells Translational s and Reviews
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