Anti-angiogenesis for cancer revisited: Is there a role for combinations with immunotherapy?

Angiogenesis is defined as the formation of new blood vessels from preexisting vessels and has been characterized as an essential process for tumor cell proliferation and viability. This has led to the development of pharmacological agents for anti-angiogenesis to disrupt the vascular supply and sta...

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Veröffentlicht in:	Angiogenesis (London) 2017-05, Vol.20 (2), p.185-204
Hauptverfasser:	Ramjiawan, Rakesh R., Griffioen, Arjan W., Duda, Dan G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Angiogenesis Inhibitors - therapeutic use Animals Antiangiogenics Biomedical and Life Sciences Biomedicine Blood flow Blood vessels Cancer Cancer Research Cardiology Cell Biology Chemotherapy Disease-Free Survival Fluid pressure Humans Hypoxia Immune checkpoint Immunosuppression Immunotherapy Immunotherapy - methods Neoplasm Proteins - immunology Neoplasms Neovascularization, Pathologic - immunology Neovascularization, Pathologic - mortality Neovascularization, Pathologic - therapy Nutrients Oncology Ophthalmology Oxygenation PD-L1 protein Permeability Receptors, Vascular Endothelial Growth Factor - immunology Review Paper Survival Rate Time dependence Tumors Vascular Endothelial Growth Factor A - immunology Viability Windows (intervals)
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