Adductome-based identification of biomarkers for lipid peroxidation

Lipid peroxidation is an endogenous source of aldehydes that gives rise to covalent modification of proteins in various pathophysiological states. In this study, a strategy for the comprehensive detection and comparison of adducts was applied to find a biomarker for lipid peroxidation-modified prote...

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Veröffentlicht in:	The Journal of biological chemistry 2017-05, Vol.292 (20), p.8223-8235
Hauptverfasser:	Shibata, Takahiro, Shimizu, Kazuma, Hirano, Keita, Nakashima, Fumie, Kikuchi, Ryosuke, Matsushita, Tadashi, Uchida, Koji
Format:	Artikel
Sprache:	eng
Schlagworte:	aldehyde Animals biomarker Biomarkers - blood Female Humans lipid oxidation Lipid Peroxidation Lipids lipoprotein Lipoproteins, LDL - blood Lysine - analogs & derivatives Lysine - blood Male Mass Spectrometry mass spectrometry (MS) Mice protein chemical modification
Online-Zugang:	Volltext
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