Adjunctive Therapies for Bacterial Keratitis
Bacterial keratitis is the most common type among all types of infectious keratitis. Currently, antibiotics are the main-stay of treatment. The objective of this systematic review is to review published clinical studies which discuss the adjunctive treatment of bacterial keratitis to guide clinical...
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Veröffentlicht in: | Middle East African journal of ophthalmology 2017-01, Vol.24 (1), p.11-17 |
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creator | Dakhil, Turki Abdulaziz Bin Stone, Donald U Gritz, David C |
description | Bacterial keratitis is the most common type among all types of infectious keratitis. Currently, antibiotics are the main-stay of treatment. The objective of this systematic review is to review published clinical studies which discuss the adjunctive treatment of bacterial keratitis to guide clinical decision-making. We reviewed the role of a variety of medications and surgeries which can help in managing bacterial keratitis complications, which include as thinning, perforation, and impaired wound healing. We have included appropriate animal and laboratory studies, case reports and case series, and randomized clinical trials regarding each therapy. |
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Currently, antibiotics are the main-stay of treatment. The objective of this systematic review is to review published clinical studies which discuss the adjunctive treatment of bacterial keratitis to guide clinical decision-making. We reviewed the role of a variety of medications and surgeries which can help in managing bacterial keratitis complications, which include as thinning, perforation, and impaired wound healing. We have included appropriate animal and laboratory studies, case reports and case series, and randomized clinical trials regarding each therapy.</description><identifier>ISSN: 0974-9233</identifier><identifier>ISSN: 0975-1599</identifier><identifier>EISSN: 0975-1599</identifier><identifier>EISSN: 0974-9233</identifier><identifier>DOI: 10.4103/meajo.MEAJO_264_16</identifier><identifier>PMID: 28546687</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. 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Jan/Mar 2017</rights><rights>Copyright: © 2017 Middle East African Journal of Ophthalmology 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484t-2a4817252409858660ed99a7be8beea2031da61fe5819938a809b497b9ed98963</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433122/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433122/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,4010,27904,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28546687$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dakhil, Turki Abdulaziz Bin</creatorcontrib><creatorcontrib>Stone, Donald U</creatorcontrib><creatorcontrib>Gritz, David C</creatorcontrib><title>Adjunctive Therapies for Bacterial Keratitis</title><title>Middle East African journal of ophthalmology</title><addtitle>Middle East Afr J Ophthalmol</addtitle><description>Bacterial keratitis is the most common type among all types of infectious keratitis. Currently, antibiotics are the main-stay of treatment. The objective of this systematic review is to review published clinical studies which discuss the adjunctive treatment of bacterial keratitis to guide clinical decision-making. We reviewed the role of a variety of medications and surgeries which can help in managing bacterial keratitis complications, which include as thinning, perforation, and impaired wound healing. We have included appropriate animal and laboratory studies, case reports and case series, and randomized clinical trials regarding each therapy.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Bacteria</subject><subject>Bacterial infections</subject><subject>Biological Dressings</subject><subject>Care and treatment</subject><subject>Cryotherapy</subject><subject>Cryotherapy - methods</subject><subject>Dosage and administration</subject><subject>Eye Infections, Bacterial - therapy</subject><subject>Gram-positive bacteria</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hyperbaric Oxygenation - methods</subject><subject>Iodine</subject><subject>Keratitis</subject><subject>Keratitis - therapy</subject><subject>Ocular Infection Update</subject><subject>Ophthalmology</subject><subject>Oxygen therapy</subject><subject>Patients</subject><subject>Respiratory therapy</subject><subject>Surgical Flaps</subject><subject>Transplants & implants</subject><subject>Ulcers</subject><issn>0974-9233</issn><issn>0975-1599</issn><issn>0975-1599</issn><issn>0974-9233</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkstu1DAUhi1ERavSF2CBRkJCLMjU98sGaVqVS1vUTVlbTnLS8SiJB9upxNvjtKXMIOyFrePv_32OfRB6Q_CSE8xOB3CbsPx-sbq8sVRyS-QLdISNEhURxrx82PPKUMYO0UlKGzwPhZXQr9Ah1YJLqdUR-rhqN9PYZH8Pi9s1RLf1kBZdiIsz12SI3vWLqxLOPvv0Gh10rk9w8rQeox-fL27Pv1bXN1--na-uq4ZrnivquCaKCsqx0UJLiaE1xqkadA3gKGakdZJ0IDQxhmmnsam5UbUpnDaSHaNPj77bqR6gbWDM0fV2G_3g4i8bnLf7J6Nf27twbwVnjFBaDD48GcTwc4KU7eBTA33vRghTssSUHKSSAhf03T_oJkxxLOXNFNaKK2z-UneuB-vHLpR7m9nUrrghuNSE57yX_6HKbGHwTRih8yW-J3i_I1iD6_M6hX7KPoxpH6SPYBNDShG658cg2M79YB_6we72QxG93X3GZ8mf32e_Af3Ort4</recordid><startdate>201701</startdate><enddate>201701</enddate><creator>Dakhil, Turki Abdulaziz Bin</creator><creator>Stone, Donald U</creator><creator>Gritz, David C</creator><general>Medknow Publications and Media Pvt. 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therapeutic use</topic><topic>Antibiotics</topic><topic>Bacteria</topic><topic>Bacterial infections</topic><topic>Biological Dressings</topic><topic>Care and treatment</topic><topic>Cryotherapy</topic><topic>Cryotherapy - methods</topic><topic>Dosage and administration</topic><topic>Eye Infections, Bacterial - therapy</topic><topic>Gram-positive bacteria</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hyperbaric Oxygenation - methods</topic><topic>Iodine</topic><topic>Keratitis</topic><topic>Keratitis - therapy</topic><topic>Ocular Infection Update</topic><topic>Ophthalmology</topic><topic>Oxygen therapy</topic><topic>Patients</topic><topic>Respiratory therapy</topic><topic>Surgical Flaps</topic><topic>Transplants & implants</topic><topic>Ulcers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dakhil, Turki Abdulaziz Bin</creatorcontrib><creatorcontrib>Stone, Donald U</creatorcontrib><creatorcontrib>Gritz, David C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - 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Currently, antibiotics are the main-stay of treatment. The objective of this systematic review is to review published clinical studies which discuss the adjunctive treatment of bacterial keratitis to guide clinical decision-making. We reviewed the role of a variety of medications and surgeries which can help in managing bacterial keratitis complications, which include as thinning, perforation, and impaired wound healing. We have included appropriate animal and laboratory studies, case reports and case series, and randomized clinical trials regarding each therapy.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>28546687</pmid><doi>10.4103/meajo.MEAJO_264_16</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Anti-Bacterial Agents - therapeutic use Antibiotics Bacteria Bacterial infections Biological Dressings Care and treatment Cryotherapy Cryotherapy - methods Dosage and administration Eye Infections, Bacterial - therapy Gram-positive bacteria Hospitals Humans Hyperbaric Oxygenation - methods Iodine Keratitis Keratitis - therapy Ocular Infection Update Ophthalmology Oxygen therapy Patients Respiratory therapy Surgical Flaps Transplants & implants Ulcers |
title | Adjunctive Therapies for Bacterial Keratitis |
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