Maintenance of the HIV Reservoir Is Antagonized by Selective BCL2 Inhibition

Decay of the HIV reservoir is slowed over time in part by expansion of the pool of HIV-infected cells. This expansion reflects homeostatic proliferation of infected cells by interleukin-7 (IL-7) or antigenic stimulation, as well as new rounds of infection of susceptible target cells. As novel therap...

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Veröffentlicht in:Journal of virology 2017-06, Vol.91 (11)
Hauptverfasser: Cummins, Nathan W, Sainski-Nguyen, Amy M, Natesampillai, Sekar, Aboulnasr, Fatma, Kaufmann, Scott, Badley, Andrew D
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Sprache:eng
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