Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain

Chronic widespread musculoskeletal pain (CWP), has a considerable heritable component, which remains to be explained. Epigenetic factors may contribute to and account for some of the heritability estimate. We analysed epigenome-wide methylation using MeDIPseq in whole blood DNA from 1708 monozygotic...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Pain (Amsterdam) 2017-06, Vol.158 (6), p.1053-1062
Hauptverfasser:	Livshits, Gregory, Malkin, Ida, Freidin, Maxim B., Xia, Yudong, Gao, Fei, Wang, Jun, Spector, Timothy D., MacGregor, Alex, Bell, Jordana T., Williams, Frances M.K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome Mapping Chronic Pain - epidemiology Chronic Pain - genetics DNA Methylation - genetics Female Genetic Association Studies Genetic Predisposition to Disease - epidemiology Genetic Predisposition to Disease - genetics Humans Male Middle Aged Musculoskeletal Pain - epidemiology Musculoskeletal Pain - genetics Neural Pathways - physiopathology Research Paper
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!