Paradoxical effect of minocycline on established neuropathic pain in rat

Neuropathic pain occurs after peripheral nerve damage, inflammation or infection. In this situation, microglial cells become activated and play a key role in producing pain. Minocycline (microglia inhibitor), was reported to reduce pain when used preventively. However, it seems that, when used after...

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Veröffentlicht in:EXCLI journal 2017-01, Vol.16, p.229-235
Hauptverfasser: Zarei, Malek, Sabetkasaei, Masoumeh, Moini-Zanjani, Taraneh
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Sprache:eng
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