Light-up probe based on AIEgens: dual signal turn-on for caspase cascade activation monitoring

Direct monitoring of multiple enzyme activities in a given biological process is extremely important for disease diagnosis. Herein, we report a single fluorescent probe that targets two caspase activities in living cells. The probe consists of three parts that includes two AIE fluorogens with distin...

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Veröffentlicht in:Chemical science (Cambridge) 2017-04, Vol.8 (4), p.2723-2728
Hauptverfasser: Yuan, Youyong, Zhang, Chong-Jing, Kwok, Ryan T K, Mao, Duo, Tang, Ben Zhong, Liu, Bin
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Sprache:eng
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