The loop hypothesis: contribution of early formed specific non-local interactions to the determination of protein folding pathways
The extremely fast and efficient folding transition (in seconds) of globular proteins led to the search for some unifying principles embedded in the physics of the folding polypeptides. Most of the proposed mechanisms highlight the role of local interactions that stabilize secondary structure elemen...
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Veröffentlicht in: | Biophysical reviews 2013-06, Vol.5 (2), p.85-98 |
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