Preexposure Prophylaxis for HIV Prevention in a Large Integrated Health Care System: Adherence, Renal Safety, and Discontinuation

BACKGROUND:Placebo-controlled and open-label studies have demonstrated the safety and efficacy of daily oral preexposure prophylaxis (PrEP) in preventing HIV infection, but data are limited on real-world PrEP use. METHODS:We conducted a cohort study from July 2012 through June 2015 of Kaiser Permane...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2016-12, Vol.73 (5), p.540-546
Hauptverfasser:	Marcus, Julia L, Hurley, Leo B, Hare, Charles Bradley, Nguyen, Dong Phuong, Phengrasamy, Tony, Silverberg, Michael J, Stoltey, Juliet E, Volk, Jonathan E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anti-Retroviral Agents - administration & dosage Anti-Retroviral Agents - adverse effects California Chlamydia Cohort Studies Delivery of Health Care, Integrated Drug abuse Drug-Related Side Effects and Adverse Reactions - epidemiology Ethnicity Female Glomerular Filtration Rate HIV HIV Infections - epidemiology HIV Infections - prevention & control Human immunodeficiency virus Humans Incidence Insurance coverage Lentivirus Male Medication Adherence Middle Aged Pre-Exposure Prophylaxis - methods Pre-Exposure Prophylaxis - statistics & numerical data Renal Insufficiency - chemically induced Renal Insufficiency - epidemiology Retroviridae Sexually transmitted diseases STD Toxicity Treatment Outcome Young Adult
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