Human genetics as a model for target validation: finding new therapies for diabetes

Type 2 diabetes is a global epidemic with major effects on healthcare expenditure and quality of life. Currently available treatments are inadequate for the prevention of comorbidities, yet progress towards new therapies remains slow. A major barrier is the insufficiency of traditional preclinical m...

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Veröffentlicht in:	Diabetologia 2017-06, Vol.60 (6), p.960-970
Hauptverfasser:	Thomsen, Soren K., Gloyn, Anna L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Diabetes Diabetes Mellitus, Type 2 - genetics Drug efficacy Drug therapy Genetic Variation - genetics Genetics Genome-wide association studies Genome-Wide Association Study Human Genetics Human Physiology Humans Internal Medicine Medicine Medicine & Public Health Metabolic Diseases Precision Medicine Review
Online-Zugang:	Volltext
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