PALADIN: protein alignment for functional profiling whole metagenome shotgun data

Whole metagenome shotgun sequencing is a powerful approach for assaying the functional potential of microbial communities. We currently lack tools that efficiently and accurately align DNA reads against protein references, the technique necessary for constructing a functional profile. Here, we prese...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2017-05, Vol.33 (10), p.1473-1478
Hauptverfasser:	Westbrook, Anthony, Ramsdell, Jordan, Schuelke, Taruna, Normington, Louisa, Bergeron, R Daniel, Thomas, W Kelley, MacManes, Matthew D
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Bacteria - genetics Bacteria - metabolism High-Throughput Nucleotide Sequencing - methods Humans Metagenomics - methods Microbiota - genetics Original Papers Sequence Alignment - methods Sequence Analysis, DNA - methods Software
Online-Zugang:	Volltext
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