Simultaneous monitoring of potassium, glucose and lactate during spreading depolarization in the injured human brain – Proof of principle of a novel real-time neurochemical analysis system, continuous online microdialysis

Spreading depolarizations occur spontaneously and frequently in injured human brain. They propagate slowly through injured tissue often cycling around a local area of damage. Tissue recovery after an spreading depolarization requires greatly augmented energy utilisation to normalise ionic gradients...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2017-05, Vol.37 (5), p.1883-1895
Hauptverfasser:	Rogers, Michelle L, Leong, Chi Leng, Gowers, Sally AN, Samper, Isabelle C, Jewell, Sharon L, Khan, Asma, McCarthy, Leanne, Pahl, Clemens, Tolias, Christos M, Walsh, Daniel C, Strong, Anthony J, Boutelle, Martyn G
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Injuries - metabolism Brain Injuries - physiopathology Coma - metabolism Coma - physiopathology Cortical Spreading Depression - physiology Electrocorticography Glucose - metabolism Humans Lactic Acid - metabolism Microdialysis Neurophysiological Monitoring - methods Online Systems Original Potassium - metabolism
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