Irisin Is Regulated by CAR in Liver and Is a Mediator of Hepatic Glucose and Lipid Metabolism

Irisin, a hormone proteolytically processed from fibronectin type III domain-containing protein 5 (FNDC5), has been reported to induce the browning of sc adipocytes by increasing the level of uncoupling protein 1. In this study, we showed that activation of the nuclear receptor constitutive androsta...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular endocrinology (Baltimore, Md.) Md.), 2016-05, Vol.30 (5), p.533-542
Hauptverfasser:	Mo, Li, Shen, Jing, Liu, Qinhui, Zhang, Yuwei, Kuang, Jiangying, Pu, Shiyun, Cheng, Shihai, Zou, Min, Jiang, Wei, Jiang, Changtao, Qu, Aijuan, He, Jinhan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Monophosphate - metabolism Adipocytes - metabolism AMP-Activated Protein Kinases - metabolism Animals Diet, High-Fat Fibronectins - metabolism Gluconeogenesis - physiology Glucose - metabolism Insulin Resistance - physiology Lipid Metabolism - physiology Lipogenesis - physiology Liver - metabolism Male Mice Mice, Inbred C57BL Mice, Obese Mice, Transgenic Nuclear Reactors Obesity - metabolism Original Research Receptors, Cytoplasmic and Nuclear - metabolism RNA, Messenger - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!