Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy

Scaffold proteins play pivotal roles in the regulation of signaling pathways, integrating external and internal stimuli to various cellular outputs. We report the pattern of cellular and subcellular expression of scaffoldins angiomotin-like 2 (AmotL2), FK506 binding protein 5 (FKBP51) and IQ motif c...

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Veröffentlicht in:	International journal of molecular sciences 2017-04, Vol.18 (4), p.891-891
Hauptverfasser:	Rotoli, Deborah, Morales, Manuel, Ávila, Julio, Maeso, María Del Carmen, García, María Del Pino, Mobasheri, Ali, Martín-Vasallo, Pablo
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Antineoplastic Agents - therapeutic use Biology Blood vessels Blood Vessels - metabolism Blood Vessels - pathology Cancer therapies Carrier Proteins - metabolism Cell cycle Cell growth Chemotherapy Colon - metabolism Colon - pathology Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Epithelial-Mesenchymal Transition Gene expression GTPase-activating protein Humans Immune system Immunohistochemistry IQGAP1 protein Kinases Liver Liver - metabolism Liver - pathology Liver cancer Liver Neoplasms - drug therapy Liver Neoplasms - metabolism Liver Neoplasms - secondary Localization Mesenchyme Metastases Metastasis Microscopy, Fluorescence Motility Neuronal-glial interactions Oncology Organoplatinum Compounds - therapeutic use Oxaliplatin Pathology Proteins ras GTPase-Activating Proteins - metabolism Scaffolds Tacrolimus Tacrolimus Binding Proteins - metabolism Tacrolimus-binding protein Tumor cells Tumorigenesis Tumors
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