Targeting the tyrosine kinase signalling pathways for treatment of immune-mediated glomerulonephritis: from bench to bedside and beyond

Glomerulonephritis (GN) affects patients of all ages and is an important cause of morbidity and mortality. Non-selective immunosuppressive drugs have been used in immune-mediated GN but often result in systemic side effects and occasionally fatal infective complications. There is increasing evidence...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2017-01, Vol.32 (suppl_1), p.i129-i138
Hauptverfasser:	Ma, Terry King-Wing, McAdoo, Stephen P, Tam, Frederick Wai Keung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal Glomerulonephritis - drug therapy Glomerulonephritis - immunology Humans Original Protein Kinase Inhibitors - therapeutic use Protein-Tyrosine Kinases - antagonists & inhibitors Protein-Tyrosine Kinases - immunology Signal Transduction - drug effects
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