Activation of MEK/ERK Signaling by PACAP in Guinea Pig Cardiac Neurons

Pituitary adenylate cyclase-activating polypeptide (PACAP) signaling can increase guinea pig cardiac neuron excitability in part through extracellular signal-regulated kinase (ERK) activation. The present study examined the PACAP receptors and signaling cascades that stimulate guinea pig cardiac neu...

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Veröffentlicht in:	Journal of molecular neuroscience 2016-06, Vol.59 (2), p.309-316
Hauptverfasser:	Clason, Todd A., Girard, Beatrice M., May, Victor, Parsons, Rodney L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Animals Biomedical and Life Sciences Biomedicine Cell Biology Colforsin - pharmacology Cyclic AMP - metabolism Cyclic AMP-Dependent Protein Kinases - metabolism Female Guinea Pigs Kinases Laboratory animals Male MAP Kinase Signaling System Myocardium - cytology Myocardium - metabolism Neurochemistry Neurology Neurons Neurons - drug effects Neurons - metabolism Neurosciences Phosphorylation Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism Polypeptides Protein Kinase Inhibitors - pharmacology Proteins Proteomics Receptors, Vasoactive Intestinal Peptide, Type II - genetics Receptors, Vasoactive Intestinal Peptide, Type II - metabolism Receptors, Vasoactive Intestinal Polypeptide, Type I - genetics Receptors, Vasoactive Intestinal Polypeptide, Type I - metabolism Signal transduction Tetradecanoylphorbol Acetate - pharmacology
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