Virucidal Activity of World Health Organization–Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses
The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activit...
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| Veröffentlicht in: | The Journal of infectious diseases 2017-03, Vol.215 (6), p.902-906 |
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| container_title | The Journal of infectious diseases |
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| creator | Siddharta, Anindya Pfaender, Stephanie Vielle, Nathalie Jane Dijkman, Ronald Friesland, Martina Becker, Britta Yang, Jaewon Engelmann, Michael Todt, Daniel Windisch, Marc P. Brill, Florian H. Steinmann, Joerg Steinmann, Jochen Becker, Stephan Alves, Marco P. Pietschmann, Thomas Eickmann, Markus Thiel, Volker Steinmann, Eike |
| description | The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations. |
| doi_str_mv | 10.1093/infdis/jix046 |
| format | Article |
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In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1093/infdis/jix046</identifier><identifier>PMID: 28453839</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><subject>Antisepsis - methods ; Brief Report ; Coronavirus Infections - prevention & control ; Ebolavirus - drug effects ; Hand Hygiene - standards ; Hemorrhagic Fever, Ebola - prevention & control ; Humans ; Middle East Respiratory Syndrome Coronavirus - drug effects ; Practice Guidelines as Topic ; Regression Analysis ; Republic of Korea ; SARS Virus - drug effects ; Severe Acute Respiratory Syndrome - prevention & control ; Virulence ; VIRUSES ; World Health Organization ; Zika Virus - drug effects ; Zika Virus Infection - prevention & control</subject><ispartof>The Journal of infectious diseases, 2017-03, Vol.215 (6), p.902-906</ispartof><rights>Copyright © 2017 Oxford University Press on behalf of the Infectious Diseases Society of America</rights><rights>The Author 2017. 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| identifier | ISSN: 0022-1899 |
| ispartof | The Journal of infectious diseases, 2017-03, Vol.215 (6), p.902-906 |
| issn | 0022-1899 1537-6613 |
| language | eng |
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| source | MEDLINE; Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Antisepsis - methods Brief Report Coronavirus Infections - prevention & control Ebolavirus - drug effects Hand Hygiene - standards Hemorrhagic Fever, Ebola - prevention & control Humans Middle East Respiratory Syndrome Coronavirus - drug effects Practice Guidelines as Topic Regression Analysis Republic of Korea SARS Virus - drug effects Severe Acute Respiratory Syndrome - prevention & control Virulence VIRUSES World Health Organization Zika Virus - drug effects Zika Virus Infection - prevention & control |
| title | Virucidal Activity of World Health Organization–Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses |
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