Vascular actions of relaxin: nitric oxide and beyond

The peptide hormone relaxin regulates the essential maternal haemodynamic adaptations in early pregnancy through direct actions on the renal and systemic vasculature. These vascular actions of relaxin occur mainly through endothelium‐derived NO‐mediated vasodilator pathways and improvements in arter...

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Veröffentlicht in:	British journal of pharmacology 2017-05, Vol.174 (10), p.1002-1014
Hauptverfasser:	Leo, C H, Jelinic, M, Ng, H H, Marshall, S A, Novak, J, Tare, M, Conrad, K P, Parry, L J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Animals Antioxidants Arteries Circulatory system Endothelium Endothelium, Vascular - metabolism Humans Kidneys Nitric oxide Nitric Oxide - metabolism Peptides Pregnancy Prostaglandins Relaxin Relaxin - metabolism Review Themed Section: Review Vascular endothelial growth factor
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