Comparison of the Mutational Profiles of Primary Myelofibrosis, Polycythemia Vera, and Essential Thrombocytosis

Abstract Objectives: To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET). Methods: Next-generation sequencing results of 75 cases of PMF, 33 cases of PV, and 27 cases of ET were compared. Results: Mutation rates o...

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Veröffentlicht in:	American journal of clinical pathology 2017-05, Vol.147 (5), p.444-452
Hauptverfasser:	Song, Jinming, Hussaini, Mohammad, Zhang, Hailing, Shao, Haipeng, Qin, Dahui, Zhang, Xiaohui, Ma, Zhenjun, Hussnain Naqvi, Syeda Mahrukh, Zhang, Ling, Moscinski, Lynn C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Aged Blood cancer Differential diagnosis DNA Mutational Analysis Female Genetic transformation High-Throughput Nucleotide Sequencing Humans Janus kinase 2 Male Middle Aged Mutation Mutation Rate Mutation rates Myelofibrosis Myeloid leukemia Next-generation sequencing Original Polycythemia Polycythemia vera Polycythemia Vera - genetics Primary Myelofibrosis - genetics Thrombocythemia, Essential - genetics Thrombocytosis
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