MicroRNA-34a targets epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion

MicroRNA-34a (miR-34a) plays an essential role against tumorigenesis and progression of cancer metastasis. Here, we analyzed the expression, targets and functional effects of miR-34a on epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs), such as TWIST1, SLUG and ZEB1/2, an...

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Veröffentlicht in:	Oncotarget 2017-03, Vol.8 (13), p.21362-21379
Hauptverfasser:	Imani, Saber, Wei, Chunli, Cheng, Jingliang, Khan, Md Asaduzzaman, Fu, Shangyi, Yang, Luquan, Tania, Mousumi, Zhang, Xianqin, Xiao, Xiuli, Zhang, Xianning, Fu, Junjiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents - pharmacology Benzoquinones - pharmacology Blotting, Western Breast Neoplasms - genetics Breast Neoplasms - pathology Cell Movement - genetics Epithelial-Mesenchymal Transition - genetics Female Gene Expression Regulation, Neoplastic - genetics Humans MicroRNAs - physiology Middle Aged Neoplasm Invasiveness - genetics Nuclear Proteins - biosynthesis Real-Time Polymerase Chain Reaction Receptor, Notch1 - biosynthesis Research Paper Transcription Factors - biosynthesis Twist-Related Protein 1 - biosynthesis Zinc Finger E-box-Binding Homeobox 1 - biosynthesis
Online-Zugang:	Volltext
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