IMGT, the international ImMunoGeneTics information system
The international ImMunoGeneTics information system® (IMGT) (http://imgt.cines.fr), created in 1989, by the Laboratoire d'ImmunoGénétique Moléculaire LIGM (Université Montpellier II and CNRS) at Montpellier, France, is a high-quality integrated knowledge resource specializing in the immunog...
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| Veröffentlicht in: | Nucleic acids research 2005-01, Vol.33 (suppl-1), p.D593-D597 |
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| creator | Lefranc, Marie-Paule Giudicelli, Véronique Kaas, Quentin Duprat, Elodie Jabado-Michaloud, Joumana Scaviner, Dominique Ginestoux, Chantal Clément, Oliver Chaume, Denys Lefranc, Gérard |
| description | The international ImMunoGeneTics information system® (IMGT) (http://imgt.cines.fr), created in 1989, by the Laboratoire d'ImmunoGénétique Moléculaire LIGM (Université Montpellier II and CNRS) at Montpellier, France, is a high-quality integrated knowledge resource specializing in the immunoglobulins (IGs), T cell receptors (TRs), major histocompatibility complex (MHC) of human and other vertebrates, and related proteins of the immune systems (RPI) that belong to the immunoglobulin superfamily (IgSF) and to the MHC superfamily (MhcSF). IMGT includes several sequence databases (IMGT/LIGM-DB, IMGT/PRIMER-DB, IMGT/PROTEIN-DB and IMGT/MHC-DB), one genome database (IMGT/GENE-DB) and one three-dimensional (3D) structure database (IMGT/3Dstructure-DB), Web resources comprising 8000 HTML pages (IMGT Marie-Paule page), and interactive tools. IMGT data are expertly annotated according to the rules of the IMGT Scientific chart, based on the IMGT-ONTOLOGY concepts. IMGT tools are particularly useful for the analysis of the IG and TR repertoires in normal physiological and pathological situations. IMGT is used in medical research (autoimmune diseases, infectious diseases, AIDS, leukemias, lymphomas, myelomas), veterinary research, biotechnology related to antibody engineering (phage displays, combinatorial libraries, chimeric, humanized and human antibodies), diagnostics (clonalities, detection and follow up of residual diseases) and therapeutical approaches (graft, immunotherapy and vaccinology). IMGT is freely available at http://imgt.cines.fr. |
| doi_str_mv | 10.1093/nar/gki065 |
| format | Article |
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IMGT includes several sequence databases (IMGT/LIGM-DB, IMGT/PRIMER-DB, IMGT/PROTEIN-DB and IMGT/MHC-DB), one genome database (IMGT/GENE-DB) and one three-dimensional (3D) structure database (IMGT/3Dstructure-DB), Web resources comprising 8000 HTML pages (IMGT Marie-Paule page), and interactive tools. IMGT data are expertly annotated according to the rules of the IMGT Scientific chart, based on the IMGT-ONTOLOGY concepts. IMGT tools are particularly useful for the analysis of the IG and TR repertoires in normal physiological and pathological situations. IMGT is used in medical research (autoimmune diseases, infectious diseases, AIDS, leukemias, lymphomas, myelomas), veterinary research, biotechnology related to antibody engineering (phage displays, combinatorial libraries, chimeric, humanized and human antibodies), diagnostics (clonalities, detection and follow up of residual diseases) and therapeutical approaches (graft, immunotherapy and vaccinology). IMGT is freely available at http://imgt.cines.fr.</description><identifier>ISSN: 0305-1048</identifier><identifier>ISSN: 1362-4962</identifier><identifier>EISSN: 1362-4962</identifier><identifier>DOI: 10.1093/nar/gki065</identifier><identifier>PMID: 15608269</identifier><identifier>CODEN: NARHAD</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adaptive immunology ; Animals ; Database Management Systems ; Databases, Genetic ; Databases, Nucleic Acid ; Databases, Protein ; Genes, Immunoglobulin ; Genes, T-Cell Receptor ; Genomics ; Humans ; Immunogenetics ; Immunology ; Innate immunity ; Internationality ; Life Sciences ; Major Histocompatibility Complex ; Protein Conformation ; Quantitative Methods ; Systems Integration ; Vertebrates - genetics ; Vertebrates - immunology</subject><ispartof>Nucleic acids research, 2005-01, Vol.33 (suppl-1), p.D593-D597</ispartof><rights>Copyright Oxford Publishing Limited(England) Jan 1 2005</rights><rights>Attribution</rights><rights>Copyright © 2005 Oxford University Press 2005</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-21670ef0522bc9608b7d8ec6d95df6760d95a04bb96af88b072b2cf57ce8b9503</citedby><orcidid>0000-0003-0116-9353 ; 0000-0002-2258-468X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC540019/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC540019/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15608269$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00018647$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Lefranc, Marie-Paule</creatorcontrib><creatorcontrib>Giudicelli, Véronique</creatorcontrib><creatorcontrib>Kaas, Quentin</creatorcontrib><creatorcontrib>Duprat, Elodie</creatorcontrib><creatorcontrib>Jabado-Michaloud, Joumana</creatorcontrib><creatorcontrib>Scaviner, Dominique</creatorcontrib><creatorcontrib>Ginestoux, Chantal</creatorcontrib><creatorcontrib>Clément, Oliver</creatorcontrib><creatorcontrib>Chaume, Denys</creatorcontrib><creatorcontrib>Lefranc, Gérard</creatorcontrib><title>IMGT, the international ImMunoGeneTics information system</title><title>Nucleic acids research</title><addtitle>Nucl. Acids Res</addtitle><description>The international ImMunoGeneTics information system® (IMGT) (http://imgt.cines.fr), created in 1989, by the Laboratoire d'ImmunoGénétique Moléculaire LIGM (Université Montpellier II and CNRS) at Montpellier, France, is a high-quality integrated knowledge resource specializing in the immunoglobulins (IGs), T cell receptors (TRs), major histocompatibility complex (MHC) of human and other vertebrates, and related proteins of the immune systems (RPI) that belong to the immunoglobulin superfamily (IgSF) and to the MHC superfamily (MhcSF). IMGT includes several sequence databases (IMGT/LIGM-DB, IMGT/PRIMER-DB, IMGT/PROTEIN-DB and IMGT/MHC-DB), one genome database (IMGT/GENE-DB) and one three-dimensional (3D) structure database (IMGT/3Dstructure-DB), Web resources comprising 8000 HTML pages (IMGT Marie-Paule page), and interactive tools. IMGT data are expertly annotated according to the rules of the IMGT Scientific chart, based on the IMGT-ONTOLOGY concepts. IMGT tools are particularly useful for the analysis of the IG and TR repertoires in normal physiological and pathological situations. IMGT is used in medical research (autoimmune diseases, infectious diseases, AIDS, leukemias, lymphomas, myelomas), veterinary research, biotechnology related to antibody engineering (phage displays, combinatorial libraries, chimeric, humanized and human antibodies), diagnostics (clonalities, detection and follow up of residual diseases) and therapeutical approaches (graft, immunotherapy and vaccinology). IMGT is freely available at http://imgt.cines.fr.</description><subject>Adaptive immunology</subject><subject>Animals</subject><subject>Database Management Systems</subject><subject>Databases, Genetic</subject><subject>Databases, Nucleic Acid</subject><subject>Databases, Protein</subject><subject>Genes, Immunoglobulin</subject><subject>Genes, T-Cell Receptor</subject><subject>Genomics</subject><subject>Humans</subject><subject>Immunogenetics</subject><subject>Immunology</subject><subject>Innate immunity</subject><subject>Internationality</subject><subject>Life Sciences</subject><subject>Major Histocompatibility Complex</subject><subject>Protein Conformation</subject><subject>Quantitative Methods</subject><subject>Systems Integration</subject><subject>Vertebrates - genetics</subject><subject>Vertebrates - immunology</subject><issn>0305-1048</issn><issn>1362-4962</issn><issn>1362-4962</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkU9v1DAQxS0EotvChQ-AVhyQQISO_yY-cKiqsrvqFnpYJMTFcrxO121iFzup6LfHIasCPdny-43fzDyEXmH4iEHSY6_j8dWNA8GfoBmmghRMCvIUzYACLzCw6gAdpnQNgBnm7Dk6wFxARYScIbm6WGw-zPudnTvf2-h174LX7XzVXQw-LKy3G2dSFpsQuz_iPN2n3nYv0LNGt8m-3J9H6Nvns83pslh_XaxOT9aF4Qz6gmBRgm2AE1IbmW3rcltZI7aSbxtRCsgXDayupdBNVdVQkpqYhpfGVrXkQI_Qp-nf26Hu7NZY30fdqtvoOh3vVdBO_a94t1NX4U5le8Ay17-b6nePqpYnazW-QcYqwco7nNm3e68Yfg429apzydi21d6GISlRUgqMjk29eQRehyEvr02KQA6CMzI6v58gE0NK0TYP9hjUmJzKyakpuQy__nfMv-g-qgwUE-Dy9n896DrejG2VXC2__1Dn9PLLBqpzdUl_Axnio1k</recordid><startdate>20050101</startdate><enddate>20050101</enddate><creator>Lefranc, Marie-Paule</creator><creator>Giudicelli, Véronique</creator><creator>Kaas, Quentin</creator><creator>Duprat, Elodie</creator><creator>Jabado-Michaloud, Joumana</creator><creator>Scaviner, Dominique</creator><creator>Ginestoux, Chantal</creator><creator>Clément, Oliver</creator><creator>Chaume, Denys</creator><creator>Lefranc, Gérard</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QO</scope><scope>7QP</scope><scope>7QR</scope><scope>7SS</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-0116-9353</orcidid><orcidid>https://orcid.org/0000-0002-2258-468X</orcidid></search><sort><creationdate>20050101</creationdate><title>IMGT, the international ImMunoGeneTics information system</title><author>Lefranc, Marie-Paule ; 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Acids Res</addtitle><date>2005-01-01</date><risdate>2005</risdate><volume>33</volume><issue>suppl-1</issue><spage>D593</spage><epage>D597</epage><pages>D593-D597</pages><issn>0305-1048</issn><issn>1362-4962</issn><eissn>1362-4962</eissn><coden>NARHAD</coden><abstract>The international ImMunoGeneTics information system® (IMGT) (http://imgt.cines.fr), created in 1989, by the Laboratoire d'ImmunoGénétique Moléculaire LIGM (Université Montpellier II and CNRS) at Montpellier, France, is a high-quality integrated knowledge resource specializing in the immunoglobulins (IGs), T cell receptors (TRs), major histocompatibility complex (MHC) of human and other vertebrates, and related proteins of the immune systems (RPI) that belong to the immunoglobulin superfamily (IgSF) and to the MHC superfamily (MhcSF). IMGT includes several sequence databases (IMGT/LIGM-DB, IMGT/PRIMER-DB, IMGT/PROTEIN-DB and IMGT/MHC-DB), one genome database (IMGT/GENE-DB) and one three-dimensional (3D) structure database (IMGT/3Dstructure-DB), Web resources comprising 8000 HTML pages (IMGT Marie-Paule page), and interactive tools. IMGT data are expertly annotated according to the rules of the IMGT Scientific chart, based on the IMGT-ONTOLOGY concepts. IMGT tools are particularly useful for the analysis of the IG and TR repertoires in normal physiological and pathological situations. IMGT is used in medical research (autoimmune diseases, infectious diseases, AIDS, leukemias, lymphomas, myelomas), veterinary research, biotechnology related to antibody engineering (phage displays, combinatorial libraries, chimeric, humanized and human antibodies), diagnostics (clonalities, detection and follow up of residual diseases) and therapeutical approaches (graft, immunotherapy and vaccinology). IMGT is freely available at http://imgt.cines.fr.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>15608269</pmid><doi>10.1093/nar/gki065</doi><orcidid>https://orcid.org/0000-0003-0116-9353</orcidid><orcidid>https://orcid.org/0000-0002-2258-468X</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Nucleic acids research, 2005-01, Vol.33 (suppl-1), p.D593-D597 |
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| subjects | Adaptive immunology Animals Database Management Systems Databases, Genetic Databases, Nucleic Acid Databases, Protein Genes, Immunoglobulin Genes, T-Cell Receptor Genomics Humans Immunogenetics Immunology Innate immunity Internationality Life Sciences Major Histocompatibility Complex Protein Conformation Quantitative Methods Systems Integration Vertebrates - genetics Vertebrates - immunology |
| title | IMGT, the international ImMunoGeneTics information system |
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