The ProDom database of protein domain families: more emphasis on 3D

ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (3D) information from the SCOP database; a completely redesigned web interface (http://www.toulouse.inra.fr/...

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Veröffentlicht in:Nucleic acids research 2005-01, Vol.33 (suppl-1), p.D212-D215
Hauptverfasser: Bru, Catherine, Courcelle, Emmanuel, Carrère, Sébastien, Beausse, Yoann, Dalmar, Sandrine, Kahn, Daniel
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Sprache:eng
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Zusammenfassung:ProDom is a comprehensive database of protein domain families generated from the global comparison of all available protein sequences. Recent improvements include the use of three-dimensional (3D) information from the SCOP database; a completely redesigned web interface (http://www.toulouse.inra.fr/prodom.html); visualization of ProDom domains on 3D structures; coupling of ProDom analysis with the Geno3D homology modelling server; Bayesian inference of evolutionary scenarios for ProDom families. In addition, we have developed ProDom-SG, a ProDom-based server dedicated to the selection of candidate proteins for structural genomics.
ISSN:0305-1048
1362-4962
1362-4962
DOI:10.1093/nar/gki034