Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism

Adrenal aldosterone excess is the most common cause of secondary hypertension and is associated with increased cardiovascular morbidity. However, adverse metabolic risk in primary aldosteronism extends beyond hypertension, with increased rates of insulin resistance, type 2 diabetes, and osteoporosis...

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Veröffentlicht in:JCI insight 2017-04, Vol.2 (8)
Hauptverfasser: Arlt, Wiebke, Lang, Katharina, Sitch, Alice J, Dietz, Anna S, Rhayem, Yara, Bancos, Irina, Feuchtinger, Annette, Chortis, Vasileios, Gilligan, Lorna C, Ludwig, Philippe, Riester, Anna, Asbach, Evelyn, Hughes, Beverly A, O'Neil, Donna M, Bidlingmaier, Martin, Tomlinson, Jeremy W, Hassan-Smith, Zaki K, Rees, D Aled, Adolf, Christian, Hahner, Stefanie, Quinkler, Marcus, Dekkers, Tanja, Deinum, Jaap, Biehl, Michael, Keevil, Brian G, Shackleton, Cedric Hl, Deeks, Jonathan J, Walch, Axel K, Beuschlein, Felix, Reincke, Martin
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