Testosterone Treatment Is a Potent Tumor Promoter for the Rat Prostate

Testosterone is increasingly prescribed to middle aged and older men, but the safety of this treatment has been called into question, and the possible risk of prostate cancer is unknown. We treated Wistar Cpb: WU rats chronically via slow-release Silastic implants with doses of testosterone that inc...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2014-12, Vol.155 (12), p.4629-4633
1. Verfasser:	Bosland, Maarten C
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens - adverse effects Animals Brief Reports Carcinogens Carcinoma - chemically induced Dose-Response Relationship, Drug Injection Male Methylnitrosourea N-Methyl-N-nitrosourea Prostate cancer Prostate carcinoma Prostatic Neoplasms - chemically induced Public health Rats Testosterone Testosterone - adverse effects Tumors
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