An ensemble-averaged, cell density-based digital model of zebrafish embryo development derived from light-sheet microscopy data with single-cell resolution

A new era in developmental biology has been ushered in by recent advances in the quantitative imaging of all-cell morphogenesis in living organisms. Here we have developed a light-sheet fluorescence microscopy-based framework with single-cell resolution for identification and characterization of sub...

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Veröffentlicht in:	Scientific reports 2015-02, Vol.5 (1), p.8601, Article 8601
Hauptverfasser:	Kobitski, Andrei Y., Otte, Jens C., Takamiya, Masanari, Schäfer, Benjamin, Mertes, Jonas, Stegmaier, Johannes, Rastegar, Sepand, Rindone, Francesca, Hartmann, Volker, Stotzka, Rainer, García, Ariel, van Wezel, Jos, Mikut, Ralf, Strähle, Uwe, Nienhaus, G. Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/328/2237 631/57/2267 Animals Cell Count Cell density Comparative studies Data Mining Datasets as Topic Developmental biology Embryo, Nonmammalian Embryonic Development - genetics Embryos Eye Fluorescence microscopy Gastrulation Humanities and Social Sciences Image Interpretation, Computer-Assisted Image Processing, Computer-Assisted Microscopy Microscopy, Fluorescence - methods Microscopy, Fluorescence - standards Morphogenesis multidisciplinary Mutation Phenotypic variations Science Subpopulations Zebrafish - genetics
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