Age-dependent regulation of GABA transmission by kappa opioid receptors in the basolateral amygdala of Sprague-Dawley rats

Anxiety disorders are one of the most common and debilitating mental illnesses worldwide. Growing evidence indicates an age-dependent rise in the incidence of anxiety disorders from adolescence through adulthood, suggestive of underlying neurodevelopmental mechanisms. Kappa opioid receptors (KORs) a...

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Veröffentlicht in:	Neuropharmacology 2017-05, Vol.117, p.124-133
Hauptverfasser:	Przybysz, K.R., Werner, D.F., Diaz, M.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Anxiety Basolateral amygdala Basolateral Nuclear Complex - drug effects Basolateral Nuclear Complex - metabolism Benzeneacetamides - antagonists & inhibitors Benzeneacetamides - pharmacology Development GABA gamma-Aminobutyric Acid - physiology Glutamic Acid - physiology Inhibitory Postsynaptic Potentials - drug effects Kappa opioid receptor Male Naltrexone - analogs & derivatives Naltrexone - pharmacology Ontogeny Pyrrolidines - antagonists & inhibitors Pyrrolidines - pharmacology Rats Receptors, Opioid, kappa - agonists Receptors, Opioid, kappa - antagonists & inhibitors Receptors, Opioid, kappa - biosynthesis Receptors, Opioid, kappa - physiology Synaptic Transmission - drug effects
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