EpCAM Intracellular Domain Promotes Porcine Cell Reprogramming by Upregulation of Pluripotent Gene Expression via Beta-catenin Signaling

Previous study showed that expression of epithelial cell adhesion molecule (EpCAM) was significantly upregulated in porcine induced pluripotent stem cells (piPSCs). However, the regulatory mechanism and the downstream target genes of EpCAM were not well investigated. In this study, we found that EpC...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2017-04, Vol.7 (1), p.46315-46315, Article 46315
Hauptverfasser:	Yu, Tong, Ma, Yangyang, Wang, Huayan
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/89 14/5 38/39 38/77 38/91 42/44 631/532/2435 631/80/79/2027 82/1 96/95 Alkaline phosphatase Animals Biomarkers Cell adhesion & migration Cell adhesion molecules Cell Line Cellular Reprogramming - genetics Epithelial Cell Adhesion Molecule - chemistry Epithelial Cell Adhesion Molecule - genetics Fibroblasts Gene expression Gene Expression Profiling Gene Expression Regulation, Developmental Gene Knockdown Techniques Humanities and Social Sciences Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Intracellular Intracellular signalling Mice Models, Biological multidisciplinary Nuclei Oct-4 protein Pluripotency Protein Binding Protein Interaction Domains and Motifs - genetics Proteolysis Science Stem cell transplantation Stem cells Swine Wnt Signaling Pathway β-Catenin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!