Fcγ receptor expression on splenic macrophages in adult immune thrombocytopenia

Summary Splenic macrophages play a key role in immune thrombocytopenia (ITP) pathogenesis by clearing opsonized platelets. Fcγ receptors (FcγR) participate in this phenomenon, but their expression on splenic macrophages and their modulation by treatment have scarcely been studied in human ITP. We ai...

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Veröffentlicht in:Clinical and experimental immunology 2017-05, Vol.188 (2), p.275-282
Hauptverfasser: Audia, S., Santegoets, K., Laarhoven, A. G., Vidarsson, G., Facy, O., Ortega‐Deballon, P., Samson, M., Janikashvili, N., Saas, P., Bonnotte, B., Radstake, T. R.
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Sprache:eng
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