Glutamine Metabolism in Cancer: Understanding the Heterogeneity

Reliance on glutamine has long been considered a hallmark of cancer cell metabolism. However, some recent studies have challenged this notion , prompting a need for further clarifications on the role of glutamine metabolism in cancer. We find that there is ample evidence of an essential role for glu...

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Veröffentlicht in:	Trends in Cancer 2017-03, Vol.3 (3), p.169-180
Hauptverfasser:	Cluntun, Ahmad A, Lukey, Michael J, Cerione, Richard A, Locasale, Jason W
Format:	Artikel
Sprache:	eng
Schlagworte:	Glutaminase - genetics Glutaminase - metabolism Glutamine - metabolism Humans Molecular Targeted Therapy Neoplasms - metabolism Neoplasms - pathology Neoplasms - therapy
Online-Zugang:	Volltext
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