Association of γH2AX at Diagnosis with Chemotherapy Outcome in Patients with Breast Cancer

γH2AX plays a role in DNA damage response signaling and facilitates the repair of DNA double strand breaks. However, it remains unknown whether constitutive tumor γH2AX expression is associated with treatment outcome in patients. γH2AX status was detected in primary tumors from 24% of 826 patients w...

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Veröffentlicht in:	Theranostics 2017-01, Vol.7 (4), p.945-951
Hauptverfasser:	Yang, Sherry X, Polley, Eric C, Nguyen, Dat
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Breast Neoplasms - diagnosis Breast Neoplasms - drug therapy Breast Neoplasms - mortality Breast Neoplasms - pathology Drug Therapy - methods Female Histones - analysis Humans Immunohistochemistry Prognosis Research Paper Survival Analysis Treatment Outcome
Online-Zugang:	Volltext
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